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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
COG3
All Species:
20.91
Human Site:
S533
Identified Species:
38.33
UniProt:
Q96JB2
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96JB2
NP_113619.1
828
94096
S533
N
S
L
T
K
S
G
S
T
E
S
L
N
P
R
Chimpanzee
Pan troglodytes
XP_001158886
790
89707
Q506
A
Q
S
L
K
D
E
Q
K
K
V
P
S
E
A
Rhesus Macaque
Macaca mulatta
XP_001096875
828
94056
S533
N
S
L
T
K
S
G
S
T
E
S
L
N
P
R
Dog
Lupus familis
XP_848489
830
94828
S535
N
N
L
T
K
S
G
S
T
E
S
L
N
P
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8CI04
820
93264
S525
S
G
L
R
K
S
G
S
T
D
S
L
N
P
R
Rat
Rattus norvegicus
NP_001012157
828
94228
S533
S
S
L
R
K
S
G
S
T
D
S
L
N
P
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417041
835
94848
S530
C
N
L
V
K
S
G
S
A
E
S
L
N
P
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001137512
820
93798
K526
L
E
E
S
E
N
K
K
L
I
S
S
D
T
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q961G1
905
101221
E521
V
S
S
A
V
E
T
E
S
V
A
T
A
Y
T
Honey Bee
Apis mellifera
XP_393867
799
92557
E499
P
I
S
R
N
H
I
E
M
D
S
I
Y
Q
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001196648
781
87158
G505
V
M
A
P
I
G
S
G
A
G
T
A
T
I
H
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_177485
784
88591
L495
N
T
T
S
E
T
D
L
R
D
D
E
N
A
D
Baker's Yeast
Sacchar. cerevisiae
P40094
801
92526
D510
I
L
P
I
S
P
N
D
A
D
D
K
S
I
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.2
98.9
95
N.A.
94.9
96.2
N.A.
N.A.
86.4
N.A.
77
N.A.
40.2
41.5
N.A.
47.5
Protein Similarity:
100
95.4
99.7
97.1
N.A.
96.9
98.1
N.A.
N.A.
92.5
N.A.
87
N.A.
56.4
60.5
N.A.
63.1
P-Site Identity:
100
6.6
100
93.3
N.A.
73.3
80
N.A.
N.A.
73.3
N.A.
13.3
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
20
100
100
N.A.
86.6
93.3
N.A.
N.A.
80
N.A.
40
N.A.
20
26.6
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
35.7
21.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
54.8
43
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
8
0
0
0
0
24
0
8
8
8
8
8
% A
% Cys:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
8
8
8
0
39
16
0
8
0
16
% D
% Glu:
0
8
8
0
16
8
8
16
0
31
0
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
8
47
8
0
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% H
% Ile:
8
8
0
8
8
0
8
0
0
8
0
8
0
16
0
% I
% Lys:
0
0
0
0
54
0
8
8
8
8
0
8
0
0
8
% K
% Leu:
8
8
47
8
0
0
0
8
8
0
0
47
0
0
0
% L
% Met:
0
8
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
31
16
0
0
8
8
8
0
0
0
0
0
54
0
0
% N
% Pro:
8
0
8
8
0
8
0
0
0
0
0
8
0
47
0
% P
% Gln:
0
8
0
0
0
0
0
8
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
24
0
0
0
0
8
0
0
0
0
0
54
% R
% Ser:
16
31
24
16
8
47
8
47
8
0
62
8
16
0
0
% S
% Thr:
0
8
8
24
0
8
8
0
39
0
8
8
8
8
8
% T
% Val:
16
0
0
8
8
0
0
0
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _